10 Best Patient Portal Software for Therapists in 2025

Managing patient care is your top priority, but the business side of practice — from scheduling to billing — often eats into your day. Sound familiar? Patient portal software aims to change that by streamlining your workflow while giving clients an easier, more secure way to stay connected.

Imagine a tool where clients can book sessions, check therapy notes, and send messages — all in one place. Beyond simplifying tasks, these portals help foster trust by offering transparency and convenience. But not all platforms are created equal. Whether you’re running a solo practice or managing a larger team, finding the right fit is key. Let’s break down the 10 most effective health coaching platforms designed to meet therapists’ needs in 2025.

Profi.io

Profi.io is an all-in-one health coaching software designed to help therapists manage and grow their practices while delivering exceptional client experiences. It offers a branded client portal where patients can schedule appointments, access educational materials, and securely communicate with their therapist. The portal also includes:

HIPAA-compliant video conferencing
Program (course) creation toolkit
Payment module, and many more

By bringing these features into one intuitive system, Profi makes it easier for therapists to focus on care while offering clients a seamless and professional experience.

Best for: Solo therapists, teams, corporate businesses and networks, aiming to provide a personalized approach while improving client satisfaction.
Price: $79 per month per seat. Profi.io offers a free trial for solo practitioners.

Schedule a personalized demo with one of our experts to discover whether Profi.io is a perfect-matched patient portal software for your clientele.

Simple Practice

Simple Practice EHR software for health & wellness offers solid tools for managing scheduling, billing, and client communication in one place, with a user-friendly interface that’s easy to navigate. The patient portal is convenient for tasks like intake forms and messaging, but the integrated billing system can be clunky, especially for handling insurance claims. While the telehealth feature is useful, it’s locked behind higher-tier plans, making it less accessible for smaller practices.

Best for: Mid-sized businesses and enterprises seeking a comprehensive, client-friendly solution to simplify practice management.
Price: Starts at $17,40 per month. Simple Practice offers a free trial.

Jane App

Jane App offers a clean, intuitive interface with robust scheduling, billing, and telehealth features, making it a reliable choice for managing a practice. Its patient portal is convenient for booking appointments and accessing receipts, but therapists dealing with insurance-heavy workflows may find the billing tools lack advanced functionality. Customization is helpful but somewhat limited, especially for larger practices with complex needs.

Best for: Small practices looking for an intuitive, all-in-one platform to manage appointments, billing, and client communication with ease.
Price: Starts at $38 per month per practitioner.

NextGen Office

NextGen Office is a robust platform for managing scheduling, billing, and telehealth, with features like customizable forms and detailed progress tracking tailored to therapists. While its billing and reporting tools are comprehensive, they can be complex and require time to learn, especially for smaller practices. The patient portal is convenient for clients, but the system’s occasional slow performance during peak times can disrupt workflows.

Best for: Therapists in mid-sized practices looking for a versatile platform to improve client communication and practice efficiency.
Price: Starts at $300.

Carepatron

Carepatron is an intuitive all-in-one EHR & practice management software that helps therapists manage scheduling, telehealth, and client communication in one place. Its flexibility allows for customizing forms, workflows, and even branding, though setting up integrations with third-party tools can sometimes be time-consuming. While the automated reminders and patient portal are convenient, occasional glitches in telehealth sessions can disrupt client interactions. For small to mid-sized practices, Carepatron is a practical choice, but larger practices with complex needs may find the reporting and billing features somewhat limited.

Best for: Small & mid-sized businesses looking for simplicity and a platform that offers essential features without overwhelming complexity.
Price: Free for solo users; paid plans start at $14 per user per month.

TheraNest

TheraNest is a reliable practice management tool for therapists, offering features like scheduling, telehealth, and integrated billing to simplify daily operations. Its patient portal makes it easy for clients to book sessions and view invoices, though the system can feel limited when managing complex insurance claims. While the interface is user-friendly, initial setup and navigation can be challenging for those less familiar with practice management software. TheraNest is a solid option for solo practitioners or small teams, though larger practices may find its scalability and reporting features less robust.

Best for: Solo practitioners and small businesses looking for a comprehensive platform that simplifies client communication and practice management.
Price: Starts at $42 per month. TheraNest offers a free trial.

Mend

Mend is a reliable telehealth platform that simplifies communication with features like video conferencing, secure messaging, and digital payments. Its patient portal is user-friendly, though customizing forms and workflows can feel limited for more complex practices. The video conferencing is generally high-quality, but occasional connectivity issues can arise, particularly with slower internet speeds. While the platform is ideal for solo or small practices focusing on telehealth, therapists managing larger teams or insurance-heavy workflows may find its tools less adaptable.

Best for: Small practices looking for a telehealth-focused platform with strong patient engagement features.
Price: Pricing available upon request.

RXNT

RXNT offers a comprehensive suite of tools for therapists, including scheduling, billing, telehealth, and a patient portal for managing appointments and communications. While the claims management system is powerful, its complexity can be overwhelming for therapists unfamiliar with insurance-heavy workflows. The reporting features are detailed, but customizing them to fit specific needs can be frustrating. Telehealth is functional, though occasional connectivity glitches and an outdated interface may hinder the user experience.

Best for: Small practices focused on insurance billing and patient management features.
Price: Starts at $110 per month per provider.

Pabau

Pabau offers a comprehensive suite of tools for therapists, including a patient portal for scheduling, treatment history, and secure messaging. Its billing and reporting features are robust, but customizing reports or navigating the marketing tools can feel unintuitive for first-time users. While the system is generally user-friendly, occasional lags during peak hours and limited flexibility in some features can frustrate therapists managing larger practices. HIPAA compliance ensures data security, but therapists with highly specialized needs may find the platform less adaptable.

Best for: Small to mid-sized practices seeking an all-in-one solution that combines client management, communication, and marketing tools.
Price: Starts at $28 per month per user.

IntakeQ

IntakeQ is a reliable platform for streamlining client onboarding, with features like secure online forms, appointment scheduling, and payment processing. Its customizable workflows and built-in telehealth tools are helpful, though setting up tailored workflows can be time-consuming for first-time users. The secure messaging and document sharing features generally work well, but occasional lags in communication can disrupt workflows. While IntakeQ’s intuitive design and HIPAA compliance make it a good fit for solo or small private-pay practices, larger practices may find its scalability limited.

Best for: Solo practitioners, small and mid-sized businesses looking for a customizable platform to enhance client onboarding and streamline practice management.
Price: Starts at $49.90 per month.

Conclusion

Choosing the right patient portal software starts with understanding your unique needs. Are you a solo therapist seeking simplicity? Options like Carepatron are excellent choices. Running a larger practice with complex workflows? Platforms like SimplePractice provide the advanced tools you need. If telehealth is central to your care, Mend is designed to streamline virtual appointments. If you need a HIPAA-compliant patient portal suitable for solo, teams, corporate teams and networks, opt for Profi.io. By focusing on what matters most to your practice — whether it’s ease of use, customization, or robust features — you can find the perfect solution to save time and enhance client relationships.